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Problems in Islam became obvious in some countries of Asia and Africa in 1990s. Manifestations of neg

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ative attitude were erupted towards France and England after 1995. The event that has to be mentioned

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

is the problem with Taliban power in Afghanistan. Osama bin Laden and Jihad created an anti-western o

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ganization al-Qaeda – it became the most violent of Islamic groups. They consider that the United Sta

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

tes is their main enemy because it is a personification of what West is described like.

Islam became

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

powerful in 1980s and 1990s and it considered that Western world is a threat because it might be dang

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

rous for their ideology and religion. The influence of Islam continued to grow after the wars in the

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

East, now there are several powerful groups there and they continue to spread their influence which i

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

very dangerous for the world.

It is almost impossible to predict how much control do Islamic groups

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

leaders have in their hands today. Islamic radical groups do not control any country completely but

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ran is the closest one to that status. And yet there are problems in Iran connected with new changes

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

such as globalization which are about to be brought to this country. There is a new movement in Islam

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

which tries to find a compromise between saving Islamic values and receiving advantages from Western

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

emocratic system in politics. The problem keep coming from conflicts between Israel and Palestine Isr

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ael and Arabia because these conflicts are not about changing religion or ideology, they are land str

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ggles. At the same time Bin Laden wants to use the conflict between Israel and Palestine to remove th

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

groups he doesn’t need from Arabia – this fact proves how such conflicts are easily used to create a

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

conflict between civilizations and danger of countries of the “First World”.

Islamic radical group

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ecame to be taken seriously after the tragedy of September,11th. Nevertheless the efforts of both Wes

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

countries and Islamist groups are needed to prevent bigger conflicts and to save peace on our planet

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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