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Psychological manipulation runs rampant through our society. People often try to get us to feel, think, say, or do things that are in their best interests by making us feel like those things are in our best interest. W

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e find it in politics, business, the media, and in social situations.

President Bush is a great manipulator: He’s full of pithy slogans designed to make us feel the way he wants us to feel. He doesn’t want us to “Cut

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

and run,” but he does want us to “Stay the course,” “Support the troops,” “Win the Peace,” “Finish the job,” and “Accomplish the mission.” When people in authority, like the president, vice-president, cabinet members,

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

congressmen, senators, and pundits repeat easy-to-remember catchphrases in different environments, our minds soon begin to remember them as truth. They are an induced regression back to childhood, where authority figure

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

s in our lives repeated what we should and shouldn’t do ad infinitum.

Big corporations are also big manipulators. They manipulate employees, suppliers, and customers. Big corporations are different than others because

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

their size gives them so much more clout. Bigger employers mean greater bargaining power because employees have fewer alternatives. Most often, they have many more people they can hire for our position than we have em

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ployers to choose from in the location and at the salary that we want. Large corporations are a big prize for suppliers that are vying for their business and both sides know it. As a result of their size, they most oft

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

en have a much greater amount of bargaining power than the companies selling to them. Large corporations also are part of an oligopoly as a result of their size. They have many times gobbled up competitors over the yea

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

rs, and spent millions on advertising and the building of their brand names to allow them to command premium prices for their products and services in the marketplace. The better a brand is known and the stronger positi

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

on it has in our minds, the more leverage a company has over us.

Television is a great tool for manipulation. Being a passive medium, it can lull us into accepting messages that we wouldn’t otherwise accept. When we w

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

atch television, most of us are looking to be entertained rather than be actively engaged in what we are doing. We are relaxing and we are absorbing. When we are in that state, we are prone to having messages imprinted

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

into us. It happens most often when we are presented with messages that have meaning to us, which cause us to experience emotions, and are expressed clearly and repeatedly.

Advertising is everywhere we turn. When we

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

watch programs on television, the characters use brand name content. We see iPods and BMWs and Pepsi logos. When we get into a car, we see ads on billboards and busses and taxis. When we go shopping, it’s on shopping

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

carts and promotional displays. When we go to a baseball game, it’s on scoreboards and outfield walls. When advertising is as pervasive as it has become, we tend to accept it, along with the rest of our environment.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

The Internet provides a tremendous opportunity for manipulators. E-mails come to us with our names in the subject lines from people we don’t know. Those subject lines appeal to our curiosity without telling us what’s

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

in the message. If we’re looking into a home-based business, the sellers often won’t even tell us what the product is or does unless we agree to hear an entire presentation. They need time to get us excited about what

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

they’re offering.

Manipulation also pervades our people relationships. The people closest to us often try to tell us what to think. They push our buttons to gain a sense of power. They’re overly nice when they feel t

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

hey have to be and not nice enough when they’re feeling secure.

The world is full of people trying to influence us. The problem comes when they push too hard and use manipulative tools to help them get what they want.

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

Powerful people and powerful organizations have a platform and bargaining power that already give them an advantage. Then, they get their messages into our heads by making them meaningful and emotional, and making them

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

clear and frequent. Our friends and family use the same techniques.

The key to dealing with manipulation is to recognize it. Once we recognize that someone is using a technique, we can deal with it more appropriately

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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People respond to certain qualities in others, and to positive statements. When you need to evoke a favorable response from anyone - family, colleague, business transaction or acquaintance these tips will set the stage for each step of the process.

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