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The dispute between Russia and the Ukraine over gas prices and supply has exposed Britain’s vulnerability of supply at the precise time our reserves are at their

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

lowest in years.

We have all been drip-fed with the story of how this winter will be the tightest yet between the supply of and the demand for gas, but who wou

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ld have believed in the distinct possibility that Britain could be left short as a result of a dispute in the Eastern block? After all, we don’t import gas dire

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tly from Russia. Our supplies come from the gas fields in the North Sea (albeit greatly depleted nowadays), the Norwegian pipeline, LNG shipped from around the w

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

orld and, increasingly, from Belgium through the Zeebrugge pipeline.

However, Russia does supply huge amounts of gas to Germany, Italy, France and Austria. We a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e increasingly dependent on Europe to supply gas to us through the Belgian pipeline and when their own supplies are threatened, which could be a real possibility

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

given the current crisis, then Europe is likely to look after itself first before turning on the flow to the UK.

The mere possibility of a threat to supplies i

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

s likely to push up the price still further than the record wholesale prices we are already experiencing.

So how did we, who were self-sufficient with our own g

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s fields and had state-run energy monopolies only 7 years ago, get into such a pickle?

The answer lies in the fact that we no longer have state-run monopolies,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

having opened our markets to ‘free competition’, whilst the rest of Europe maintained their monopolistic structures.

Their sheer size enabled them to march into

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

the UK and virtually uncontested, acquire the bulk of our energy suppliers. But despite huge protests from the UK, and in particular, the remaining UK heavyweigh

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

t Centrica, they have been able to protect their own markets and all sources of supply.

It’s no surprise, then, that a recent survey of British businesses has p

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ointed the finger at the Government for the huge rises in energy prices despite Gordon Brown’s efforts to pin the blame on market forces and the failure of OPEC

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

o step up oil production in response to escalating global demand.

Things could have been so different. The idea of bringing competition into the market is a sou

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

nd one. However, mistakes were made by allowing huge companies to get involved in generation, distribution and retail. By doing so, they were able to secure a st

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

onghold. Foreign conglomerates were allowed to walk away with the energy crown jewels and by participating in this sell off our government effectively compromise

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

d our security of supply.

Impact on business electricity

The business sector has been dealt a double whammy. Firstly, there’s no running away from the fact tha

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

t having to buy gas from Europe to replace indigenous supplies will add to the wholesale price of gas, and therefore, electricity. When the supply to Europe is b

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ing affected by the dispute then the price will rise further still.

But to rub salt in the wound, many businesses are experiencing rises well above those that m

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ay be justified by the rise in wholesale prices and since the market is dominated by the big 6 suppliers businesses have little muscle to negotiate better prices

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Social Articles - Government Pins Blame on Market Forces For GB Energy Crisis

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