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Denver Colorado is a large metropolitan area consisting of over two million people. According to the U.S. poll taken in 2000 there are approximately 720 thousand minority individuals in the area. Mino

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rity relations are reliant not only on existing communications between groups, they’re also influenced by events that may have occurred decades or even generations before. Although these actions may oc

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

upy no present members of minority or majority groups, recollections of bigotry are long and often color perceptions of present group dealings.

While the city of Denver is relatively young, having been

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

incorporated in 1858, it has had a checkered history of dealing with minority groups.

In the year 1864, Colonel John Chivington led a group of Colorado volunteer militia against a peaceful Arapahoe an

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Cheyenne Indian camp located west of Denver. Using both cavalry and cannon, they effectively wiped out this camp, killing an estimated 150 men, women, and children. History has recorded many of the v

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ry gruesome details of torture and corpse disfigurement committed and bragged about by the militia. This incident, now known as The Sand Creek Massacre, was widely celebrated in Denver as a major victo

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ry in the Indian wars.

In the year 1914, the governor of Colorado sent Colorado militia to obliterate a coalmine workers camp located south of Pueblo Colorado near a coalmine owned by J. D. Rockefeller

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

Attacking with machine guns and an armored car, the militia killed twenty people, including twelve women and children. The Denver newspapers reported this as a victory over immigrant miners, who were

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

being completely unreasonable in their demands against an American mining company. It is now known nationally as the Ludlow Massacre.

From a personal standpoint, I can state that minority issues do n

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t have a very direct effect on me. As a member of the majority group, my interactions with minority group members are somewhat limited. Although there are a few Asian families living in my neighborhoo

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

, they tend to keep to themselves and so interactions are limited to a quick “Hi”, or wave. Not being exposed to many minority group members has the affect of desensitizing me to many racial issues. I

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

, like many members of the majority group may feel that I am completely fair in all of my thoughts and actions regarding racial interactions. But the fact that we so seldom have a need to place this in

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

o practice, may show that there are racial issues that we simply have not recognized. The most directly visible effect race relations has on me, is in the voting booth. That is, should I vote for or a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

gainst minority issues? What are the costs? What are the benefits? I may read a newspaper story regarding a racial issue, and think that isn’t fair, or there should be a law, but as it doesn’t really

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

affect me, that’s as far as it goes. However, ignoring racial issues does not a great city make.

Certainly, many racial and prejudicial issues could be addressed in the Denver area. Any time you have

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

minorities representing 30% of the population, their needs should be given consideration by the majority group. Providing equal education opportunities as well as programs specifically tailored to incr

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ease minority graduation rates would certainly be the first thing to change. Requiring cultural diversity training for police officers, to bring an end to racial profiling would be second. Developing

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ommunity programs to give minority teens an alternative to drugs and gangs would help to ensure the new generation a strong place in American society.

Without a radical change in our immigration polici

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

es, we will see the percentage of minorities in our communities continue to increase in the years to come. We must accept this fact and work to reduce the amount of racial and prejudicial discriminatio

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

minority groups face. We must also assist in their assimilation into American society. This will help to ensure that America continues as a strong vibrant nation with a diverse yet cohesive population

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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