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Analysing the potential impact the Alberta's oilsands reserves could have on the world oil market requires one to clarify what volumes regarding available reserves and output will be used in discussion. Determining the size or clarifying which data sets are used is la

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rgely dependant on a variety of variables and measures a particular firm or institution incorporates. According to The Alberta Energy and Utilities Board (EUB), current oilsands reserves are estimated to contain approximately 174 billion barrels oil (as of 2003). 174

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

illion barrels of available reserves producible at current technology. Many advocates of the oilsands production and expansion, that is producers and Alberta politicians alike, are eager to divulge a resource value closer to 315 billion barrels. This ultimate recovera

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ble volume is attractive to proponents of oilsands production because of its size. The ultimate recoverable estimate is greater than the current conventional proved oil reserve estimate for Saudi Arabia, OPEC's biggest member and producer. However, using the ultimate

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

esource figure when describing the current potential for Alberta oilsands output is presumptuous. The value cannot be supported with current technology and thus should not be considered when determining the size of the resource. The more accurate estimate suggests Alb

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

rta holds the world's second largest reserve of oil deposits at 174 billion barrels. Although the ultimate potential of the oilsands is comforting to Albertans, due to their dependency on the energy sector, the value of current recoverable reserves is nonetheless stag

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

gering when compared to the remaining conventional reserves within Alberta and abroad as well.

This is the primary reason why the oilsands have generated significant interest, the volume of reserves will meet Alberta's appetite for oil revenues and America's appetite

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

for oil consumption for years to come. Thus the question is: are the reserves large enough to meet and impact the world oil market prices and can this supply reduce America's need for Middle East oil? Without a doubt the oilsands deposits are large enough to support

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

an increase in production and consequently an increase in exports to the world market (the closest market being America). Will producers be able increase oilsands extraction technology to make it less costly to lift and more efficient, thus increasing output? One woul

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

assume they can, the energy industry increases their own longevity by repeatedly devising new and efficient techniques and protocols. Although this theory sounds simple, it is missing an integral component that can ultimately dictate whether oilsands production will

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

it boom or bust, and that is the dependence on world market price. The likes of Shell, Suncor, Nexen, to name a few, are continually expanding their operations to accommodate the growing world demand, and to exploit the resource, however, these firms will only expand

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

if it remains profitable for them. Oilsands production is very capital intensive and requires ideal market conditions to render them appealing to investors. Regardless of world supply depletions, increases in world demand, or size of Alberta's reserves, market price i

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

what will plot the future of oilsands development and production. Thus the only item holding the emergence of oilsands 'dominance' on the world market is the level of output and dependence on market price. What do we experience today? (2006) Record crude oil prices w

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ith no indications they will relent. Supply is tight and OPEC is happy with this state. If Alberta and oilsands are to have any substantial impact on the world stage they must increase technology (reducing costs) and production (increasing volume).

Three essential it

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ms are required for successful integration of oilsands products into the world market. Firstly, oilsands producers need to increase production technology to reduce lifting costs. Attributed to costs is the ability for producers to locate dedicated and cost efficient t

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ansportation methods to place their product on the world market. The second item will hinge upon the world price of oil. Currently the oilsands developers are price takers. It is imperative that a costly venture such as oilsands production continue to exploit a high w

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

orld oil market price to justify their production and expansion. Current market conditions, the high market price for crude, make for an ideal setting for expansion and development. Expanding technology will reduce costs of production thereby shielding producers from

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ower market prices and increasing their overall productivity. A strong and predictable price will provide the foundation for continual expansion of oilsands production, and thus building Alberta's position in the world market. The last item depends on both technology

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

and price-that is the quantity of output. Currently, Alberta produces approximately 352 million barrels of crude oil a year from the bitumen reserves. The current production volume is not enough to have even a minimal impact on OPEC's world market share. If the entire

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

volume from 2003 output was exported to the United States market, this would account for less than 30 days worth of their yearly imports. Although this may be a large quantity, the potential is greater still.

This article is continued in Part 2 which is now available

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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