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An OSPF adjacency can be authenticated with MD5 (Message Digest 5) or with a clear-text password. I’m not much on clear-text passwords, and hopefully you aren’t eithe

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

r! Whether you’re working in the real world or the certification exam room, though, it’s always a good idea to know more than one way to do things. Let’s take a look

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

at how to configure clear-text authentication of an OSPF neighbor relationship.

The commands we’ll use are “ip ospf authentication-key” and “ip ospf authentication”.

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

In this example, we have preexisting adjacencies between three routers in an OSPF NBMA network. The hub router (R1) has an adjacency with two spoke routers, R2 and R

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

3.

The password is set by the interface-level command ip ospf authentication-key. While Cisco routers will usually tell you when you’re about to try to do something

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

that you can’t do, this password is a rare exception to the rule. Let’s set a password of passbscitest and then check the router config.

R1(config-if)#ip ospf authen

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

tication-key ?

<0-7> Encryption type (0 for not yet encrypted, 7 for proprietary)

LINE The OSPF password (key)

R1(config-if)#ip ospf authentication-key passbscitest

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

R1#show config

interface Serial0

ip address 172.12.123.1 255.255.255.0

encapsulation frame-relay

ip ospf authentication-key passbsci

I entered a 12-character pa

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ssword, but only the first eight are showing in the router configuration. The router failed to warn us that this particular password has a limit of eight characters.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

As of IOS 12.4, the router now warns the admin about this, but there are plenty of routers out there that aren’t running that recent a release!

Clear-text authentica

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

tion is enabled with the ip ospf authentication command. IOS Help shows there is no specific command for clear-text authentication. (Null and clear-text authenticati

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

on are not the same thing.)

R1(config)#int serial0

R1(config-if)#ip ospf authentication ?

message-digest Use message-digest authentication

null Use no authenticati

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

on

< cr >

To set clear-text authentication, just use the basic command with no options.

R1(config-if)#ip ospf authentication

About two minutes after entering that

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

configuration, the preexisting adjacencies go down:

R1#

00:25:38: %OSPF-5-ADJCHG: Process 1, Nbr 172.12.123.2 on Serial0 from FULL to DOWN, Neighbor Down: Dead timer

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

expired

R1#

00:25:58: %OSPF-5-ADJCHG: Process 1, Nbr 172.12.123.3 on Serial0 from FULL to DOWN, Neighbor Down: Dead timer expired

R1#

Until we configure the spoke

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

routers with the same config, the adjacencies will stay down – so let’s get those spokes configured!

R2(config)#interface serial0

R2(config-if)#ip ospf authenticati

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

on-key passbsci

R2(config-if)#ip ospf authentication

R3(config)#interface serial0

R3(config-if)#ip ospf authentication-key passbsci

R3(config-if)#ip ospf authentic

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ation

On R1, show ip ospf neighbor verifies that the adjacencies are back up.

R1#show ip ospf neighbor

Neighbor ID Pri State Dead Time Address Interface

172.12.123

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

.3 0 FULL/DROTHER 00:01:58 172.12.123.3 Serial0

172.12.123.2 0 FULL/DROTHER 00:01:37 172.12.123.2 Serial0

Now that you know how to configure OSPF neighbor authentica

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

tion in clear text, you need to learn how to use MD5 authentication, and that just happens to be the subject of my next CCNP BSCI 642-901 exam tutorial! See you then!

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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