Social Articles - Writing and Speaking

FORWARD

The 188 stage Hero's Journey (Monomyth) is the template upon which the vast majority of successful stories and Hollywood blockbusters are bas

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ed upon. In fact, ALL of the hundreds of Hollywood movies we have deconstructed (see URL below) are based on this 188+ stage template.

Understanding

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

his template is a priority for story or screenwriters. This is the template you must master if you are to succeed in the craft.

[The terminology is m

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ost often metaphoric and applies to all successful stories and screenplays, from The Godfather (1972) to Brokeback Mountain (2006) to Annie Hall (1977

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

to Lord of the Rings (2003) to Drugstore Cowboy (1989) to Thelma and Louise (1991) to Apocaplyse Now (1979)].

THERE IS ONLY ONE STORY

THE 188 STAGE

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

HERO'S JOURNEY:

a) Attempts to tap into unconscious expectations the audience has regarding what a story is and how it should be told.

b) Gives the

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

writer more structural elements than simply three or four acts, plot points, mid point and so on.

c) Gives you a tangible process for building and re

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

leasing dissonance (establishing and achieving catharses, of which there are usually four).

d) Tells you what to write. For example, at a certain sta

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e of the story, the focus should be on the Call to Adventure and the micro elements within.

ABRIDGED TIPS, EXCERPTS AND EXAMPLES:

(simply go to http

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

://www.screenplay-structure.com/ or http://www.story-structure.org/ for full details)

*****Dissatisfaction*****

Part of the Period of Desolation. Be

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ore the Hero commits to the Journey and Transformation or is forced to by an Unbearable Antagonism, dissatisfaction and frustration sets in. In Brokeb

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ack Mountain (2005), Enis asks "...why didn’t we get the powdered milk...."

*****Disgust*****

Disgust is a core part of the Refusal, post the Ultima

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e Boon. The Hero (or major character) is disgusted by what he (or she) has become or was. It is a reaction to the Transformation so far. In Bonnie and

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

Clyde (1967), Blanche regrets the path she has chosen.

*****Mentor's Backstory*****

The Mentor's Backstory is often made explicit. In Bonnie and Cl

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

de (1967), Clyde tells Bonnie he cut part of his foot off.

*****Marker of Change*****

Change is in the air and it is illustrated by a marker (before

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

embarking on the Road of Trials). In Dances with Wolves (1990), the buffalo arrive. In Godfather (1972), the exchange of gifts and the chaperones for

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

shadow a new beginning. In Romancing the Stone (1984), Joan looks at Jack with bedroom eyes.

*****Push to the Crossing of the Return Threshold*****

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

The Rescue from Without pushes the Hero to the Return Crossing. In Brokeback Mountain (2005), "...is your Daddy the marrying kind?"

*****Conscious De

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ision*****

The conscious Decision (almost an Accepting the Inevitability of the Journey and Transformation) is a very common part of successful stori

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

es and screenplays. In Brokeback Mountain (2005), Jack says hello to Ennis; that they will be spending time up on the mountaion together is inevitable

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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