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    The 188 stage Hero's Journey (Monomyth) is the template upon which the vast majority of successful stories and Hollywood blockbusters are based upon. In fact, ALL of the hundreds of Hollywo
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    od movies we have deconstructed (see URL below) are based on this 188+ stage template.

    Understanding this template is a priority for story or screenwriters. This is the template you must master if
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ou are to succeed in the craft.

    [The terminology is most often metaphoric and applies to all successful stories and screenplays, from The Godfather (1972) to Brokeback Mountain (2006) to Annie Hall
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    (1977) to Lord of the Rings (2003) to Drugstore Cowboy (1989) to Thelma and Louise (1991) to Apocaplyse Now (1979)].

    THERE IS ONLY ONE STORY

    THE 188 STAGE HERO'S JOURNEY:

    a) Attempts to tap into
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    nconscious expectations the audience has regarding what a story is and how it should be told.

    b) Gives the writer more structural elements than simply three or four acts, plot points, mid point and
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    so on.

    c) Gives you a tangible process for building and releasing dissonance (establishing and achieving catharses, of which there are usually four).

    d) Tells you what to write. For example, at a
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    ertain stage of the story, the focus should be on the Call to Adventure and the micro elements within.

    ABRIDGED TIPS, EXCERPTS AND EXAMPLES:

    (simply go to easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    urney.info/">http://www.heros-journey.info/ for full details)

    *****Pushed out of the Cave*****

    Pushes and Pulls are an underrated aspect of storytelling. Pushes and Pulls force the Hero et al
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    rom one stage of the journey to the next.

    The Hero et al are pushed or pulled out of the Cave. In Dances with Wolves (1990), John Dunbar is pulled out of his solitary life in Fort Hayes by the arri
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    al of the Indians. In Bonnie and Clyde (1967), both protagonists go on the run because they've killed someone.

    *****Rebirth*****

    The Rebirth follows the Near Death Experience. In Brokeback Mountai
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    (2005), Jack and Lureen (everyone) are older (the parker sequence). Ennis and Alma are older too (Ennis forgets his fishing gear).

    *****Pushed out of the Cave*****

    Pushes and Pulls are an underra
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    ted aspect of storytelling. Pushes and Pulls force the Hero et al from one stage of the journey to the next.

    The Hero et al are pushed or pulled out of the Cave. In Dances with Wolves (1990), John
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    unbar is pulled out of his solitary life in Fort Hayes by the arrival of the Indians. In Bonnie and Clyde (1967), both protagonists go on the run because they've killed someone.

    *****Seizing the Sw
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    rd and Expansion of Consciousness*****

    The Seizing of the Sword stage is a multistaged process. Two aspects include the Seizure of the Sword (a tangible metaphor) and the Expansion of Consciousness
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    which often manifests itself in the gaining of an insight or a capability that was previously non-existent. In Straw Dogs (1971), David shoots the bird easily and is sorry.

    *****Romantic Challenge
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    Polarized*****

    The Romantic Challenge is just that - a challenge that has to be resolved. As such, the Hero and Romantic Challenge are, at first meeting, highly polarized. In Raiders of the Lost Ar
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    (1981), Marion argues with Indy outside her bar. In The Deer Hunter (1978), Michael is a world away from Linda. In The English Patient (1996), Laszlo and Katharine have the problem of her husband.
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    *****Conscious Agreement*****

    The Hero consciously agrees to Journey and Transform, post the Unbearable Antagonism. Methods include:

    Explicit Statement. An Explicit Statement or Declaration of Int
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    nt is heard. In The Matrix (1999), Neo has a choice between the blue and red pill. In Star Wars (1977), Luke explicitly states that he wants to join Obi Wan and become a Jedi Knight like his father.
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip

    Implicit Statement. Even if the Hero is unwilling, the Explicit Statement may be implicit in the Hero's action. In Gladiator (2000), Maximus' family has been brutally murdered. He will seek revenge


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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