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The 188 stage Hero's Journey (Monomyth) is the template upon which the vast majority of successful stories and Hollywood blockbus

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ters are based upon. In fact, ALL of the hundreds of Hollywood movies we have deconstructed (see URL below) are based on this 188+ stage t

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

mplate.

Understanding this template is a priority for story or screenwriters. This is the template you must master if you are to succeed

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

in the craft.

[The terminology is most often metaphoric and applies to all successful stories and screenplays, from The Godfather (1972)

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

o Brokeback Mountain (2006) to Annie Hall (1977) to Lord of the Rings (2003) to Drugstore Cowboy (1989) to Thelma and Louise (1991) to Apo

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

caplyse Now (1979)].

THERE IS ONLY ONE STORY

THE 188 STAGE HERO'S JOURNEY:

a) Attempts to tap into unconscious expectatio

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

s the audience has regarding what a story is and how it should be told.

b) Gives the writer more structural elements than simply three or

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

four acts, plot points, mid point and so on.

c) Gives you a tangible process for building and releasing dissonance (establishing and ach

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

eving catharses, of which there are usually four).

d) Tells you what to write. For example, at a certain stage of the story, the focus sh

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ould be on the Call to Adventure and the micro elements within.

ABRIDGED TIPS, EXCERPTS AND EXAMPLES:

(simply go to

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

="http://www.heros-journey.info/">http://www.heros-journey.info/ for full details)

*****Final Conflict - Shape Shifter Revealed*****

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

During the Final Conflict, post the Shape Shifter's Period of Dissonance, he (or she) must decide. In Bonnie and Clyde (1967), Blanche rev

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

eals Moss' surname.

*****Antagonism of the New World*****

When the Hero et al arrive in the New World, it is not uncommon for it to be a

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

normal domain of the Antagonism. In Straw Dogs (1971), David and Amy say hello to Charlie.

*****Loop*****

Though not critical, it is use

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ful to keep in mind the concept of the loop, which is most often used to neatly close a story (which does not necessarily mean that all ch

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

llenges are resolved). The very first sequences link to the very last.

Often the loop is closed once the Hero has completed his (or her)

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

Journey and returns to his or her Ordinary World. In the Lord of the Rings trilogy, Frodo et al return to the idyllic (and now safe) Shire

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

In The Great Escape (1963), Hilts and some of the other prisoners return to the camp.

When the Hero does not return back to the Ordinary

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

World, other techniques are often used to close the story. In War of the Worlds (2005), the initial and final images are those of bacteri

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

, neatly closing the story. In Drugstore Cowboy (1989), Bob tells us his story on the way to the hospital - the opening and closing scenes

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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